Bottom line: While the rodent study
by Zhang et al. appears to support the accuracy of the data Vinson et
al. published two years ago, you as a SuppVersity reader should
be aware of the fact that the reduction in cortisol / cortisone activity
Revuelta-Iniesta and Al-Dujaili observed in their subjects is not
necessarily going to facilitate weight loss. As discussed in the
corresponding Science Round Up, a normal circadian cortisol rhythm with both
spikes and troughs is a prerequisite of optimal fat loss, so that it's
suppression by green coffee beans or other means is beneficial only for
those of us who suffer from chronically elevated cortisol levels.
Overall, we are thus left with a single study the whole "green coffee
bean for weight loss"-hype is based on. Well, who cares. For the
majority of best-selling supplements we don't even have that ;-)
References:
- Jaquet, Muriel, et al. "Impact of coffee consumption on the gut
microbiota: a human volunteer study." International journal of food
microbiology 130.2 (2009): 117-121. - Revuelta-Iniesta, R., and E. A. S. Al-Dujaili. "Consumption of Green
Coffee Reduces Blood Pressure and Body Composition by Influencing
11β-HSD1 Enzyme Activity in Healthy Individuals: A Pilot Crossover Study
Using Green and Black Coffee." BioMed Research International 2014
(2014). - Vinson, Joe A., Bryan R. Burnham, and Mysore V. Nagendran.
"Randomized, double-blind, placebo-controlled, linear dose, crossover
study to evaluate the efficacy and safety of a green coffee bean extract
in overweight subjects." Diabetes, metabolic syndrome and obesity:
targets and therapy 5 (2012): 21. - Zheng, et al. "Chlorogenic acid and caffeine in combination inhibit fat accumulation by
regulating hepatic lipid metabolism-related enzymes in mice." British Journal of Nutrition (2014). Ahead of Print.
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