Monday, September 15, 2014

SuppVersity - Nutrition and Exercise Science for Everyone: Creatine: Benefits Accumulate - Now it Prevents NA...

SuppVersity - Nutrition and Exercise Science for Everyone: Creatine: Benefits Accumulate - Now it Prevents NA...: Creatine is a dangerous steroid? Well, the study at hand shows that it will prevent not promote hepatic lipid accumulation as you will see...

Bottom line: The study at hand adds weight to the previously formulated hypothesis that creatine supplementation (obviously cheap, but pure creatine monohydrate) is not for muscle-headz, only.

Figure 3: Creatine monohydrate supplementation increases glucose uptake via GLUT-4 receptor expression in immobilized and active human skeletal muscle (Op't Eijnde. 2001)

On the contrary! In conjunction with the previously established anti-oxidant effects and its ability to improve glucose management via increases in AMPK and GLUT-4 (glucose receptor) expression in skeletal muscle cells (see Figure 3), the data from this recent study by scientists from the University of Alberta should eventually shut the critics, who still claim creatine was a "dangerous steroid" or at least a "gateway drug to steroid abuse" up. Unfortunately, something in the back of my head tells me that studies are less convincing to the medical orthodoxy than the glossy product flyers for the latest patentable diabesity and NAFLD drugs | Comment on Facebook!

References:

da Silva, Robin, Karen Kelly, and Rene Jacobs. "Hepatic carbohydrate and lipid metabolism are altered in rats fed creatine-supplemented diets (LB151)." The FASEB Journal 28.1 Supplement (2014a): LB151.
da Silva, Robin P., et al. "Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids (2014b).
Engelhardt, Martin, et al. "Creatine supplementation in endurance sports." Medicine and Science in Sports and Exercise 30.7 (1998): 1123-1129.
Jacobs, Rene L., Robin da Silva, and Randy Nelson. "Creatine Supplementation may prevent NAFLD by stimulating fatty acid oxidation." The FASEB Journal 27 (2013): 222-2.
Op't Eijnde, B., et al. "Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization." Diabetes 50.1 (2001): 18-23.

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